So far, two patients have had the operation, and early indications are 'promising', with both eating less and losing weight.
The surgery was performed by Dr Donald Whiting, a neurosurgeon at West Virginia University Hospital. Dr Whiting admits it is a drastic procedure - 'but obesity is a drastic problem'.
He adds: 'There is a risk of stroke and death from this operation, but this is slight. These patients are probably at greater risk of heart attack and stroke from being obese.'
Only patients who've tried every other treatment, including gastric surgery (such as a gastric band or bypass), are considered for DBS. But Dr Whiting believes the new approach makes greater sense than other surgery.