It was Doctor Matthew During, MD, PhD of Ohio State University Medical Center who developed the concept, using a gene in lab mice known as BDNF. "We're putting in a normal, healthy copy of the gene that's already there, but just giving it the instructions to turn it on so that gene is now what we call being expressed," says Dr. During. And when it is expressed, that gene helps control not only how much the animals eat but how efficiently they burn calories.
Clinical trials involving mice yielded impressive results. Within an hour of injection, insulin levels in the mice dropped by a third. Within weeks of injection, the mice shed half their weight. All from a single injection.
Read more: Medical News Today